Chromosome Aberrations Test
(Also chromosome mutation test, of MS – a progressional control of the Kluge therapy)
Chromosome aberrations also serve the determination of geno toxicity tests in materials and food. In the case of MS there should be proof that toxic working metabolism metabolites, like intermediary formation ammonia, have caused changes in the genetic material and if so whether these changes can be reversed. On the breaking line of the DNS spiral (chromatides aberration), in the sense of the working hypothesis, the alpha helix structure becomes a beta fold structure.[1,2,3,4].
The question arises, whether this genetic defect can be made reversible through the Kluge therapy ? Are the chromatide breaks of the 23 autosome pairs (Autosomenpaare) to be seen in context for the process activity of the auto agressiv immunsystem? (HLA-Loci).
Initial observations and examination results verify the assumption that increased chromosome breaks of MS patients are depictabel. Can this destruction be repaired through the Kluge therapy?
The cyto genetic results of the Kluge therapy group go along with the registered positive clinical and neurological result changes.
Results:
In 2002 blood samples from 12 patients were taken an examined in the cyto genetic laboratory of Frau Dr. Lydia Werner in Halle/Saale, Germany. The patients were not differentiated as to the course of progression or severity. They had all completed therapies with steroids and immune modulated medicine.
Number of the chromosome breaks before therapy: 3 to 7 (ø = 5,3) (n = 12)
Number of the chromosome breaks after 6-9 months: 0 to 1 (ø = 0,8) (n = 12)
The spontaneous rate of mutation of a similar population is in the region of 0.6% and 4 %.
Through the determining of the chromosome aberration before and after the Kluge therapy took hold, it’s effectiveness could be confirmed.